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| Player | Mat | Runs | HS | 100 | 50 | |
| JM Bairstow (Eng) | 3 | 219 | 124 | 1 | 1 | |
| KL Rahul (Ind) | 3 | 177 | 108 | 88.50 | 1 | 1 |
| Shikhar Dhawan (Ind) | 3 | 169 | 98 | 0 | 2 | |
| RR Pant (Ind) | 2 | 155 | 78 | 0 | 2 | |
| BA Stokes (Eng) | 3 | 135 | 99 | 0 | 1 | |
| Virat Kohli (Ind) | 3 | 129 | 66 | 0 | 2 | |
| Jeson Roy (Eng) | 3 | 115 | 55 | 38.33 | 0 | 1 |
| SM Curran (Eng) | 3 | 107 | 95* | 0 | 1 | |
| HH Pandya (Ind) | 3 | 100 | 64 | 0 | 1 |
| Player | Wkts | Mat | Runs | BBI |
| SN Thankr (Ind) | 7 | 3 | 158 | 4/67 |
| B Kumar (Ind) | 6 | 3 | 135 | 3/42 |
| MP Krishna (Ind) | 6 | 3 | 174 | 4/54 |
| Mark Wood (Eng) | 5 | 2 | 109 | 3/34 |
| BA Stokes (Eng) | 4 | 3 | 121 | 3/34 |
| Player | Runs | Venue | Date |
| JM Bairstow (Eng) | 124 | Pune | 26 Mar 2021 |
| KL Rahul (Ind) | 108 | Pune | 26 Mar 2021 |
| BA Stokes (Eng) | 99 | Pune | 26 Mar 2021 |
| Sam Curran (Eng) | 95* | Pune | 28 Mar 2021 |
| Shikhar Dhawan (Ind) | 98 | Pune | 23 Mar 2021 |
| JM Bairstow (Eng) | 94 | Pune | 23 Mar 2021 |
| RR Pant (Ind) | 78 | Pune | 28 Mar 2021 |
| RR Pant (Ind) | 77 | Pune | 26 Mar 2021 |
| S Dhawan (Ind) | 67 | Pune | 28 Mar 2021 |
| Virat Kohli (Ind) | 66 | Pune | 26 Mar 2021 |
| HH Pandya (Ind) | 64 | Pune | 28 Mar 2021 |
| KL Rahul (Ind) | 62* | Pune | 23 Mar 2021 |
| KH Pandya (Ind) | 58* | Pune | 23 Mar 2021 |
| Virat Kohli (Ind) | 56 | Pune | 23 Mar 2021 |
| Player | 6s | Mat | Runs | HS |
| JM Bairstow (Eng) | 14 | 3 | 219 | 124 |
| Ben Stokes (Eng) | 11 | 3 | 135 | 99 |
| RR Pant (Ind) | 11 | 2 | 155 | 78 |
| HH Pandya (Ind) | 8 | 3 | 100 | 64 |
| KL Rahul (Ind) | 6 | 3 | 177 | 108 |
| Player | 50s | Mat | Runs | HS |
| Virat Kohli (Ind) | 2 | 3 | 129 | 66 |
| RR Pant (Ind) | 2 | 2 | 155 | 78 |
| Shikhar Dhawan (Ind) | 2 | 3 | 169 | 98 |
| BA Stokes (Eng) | 1 | 3 | 135 | 99 |
| JM Bairstow (Eng) | 1 | 3 | 219 | 124 |
| KL Rahul (Ind) | 1 | 3 | 177 | 108 |
| KH Pandya (Ind) | 1 | 3 | 95 | 58* |
| Jeson Roy (Eng) | 1 | 3 | 115 | 55 |
| HH Pandya (Ind) | 1 | 3 | 100 | 64 |
| Sam Curran (Eng) | 1 | 3 | 107 | 95* |
| Player | 100s | Mat | Runs | HS |
| KL Rahul (Ind) | 1 | 3 | 177 | 108 |
| JM Bairstow (Eng) | 1 | 3 | 219 | 124 |
| Team | Score | Ovrs | RR | Venue | Date |
| England | 337/4 | 43.3 | 7.74 | Pune | 26 Mar 2021 |
| India | 336/6 | 50.0 | 6.72 | Pune | 26 Mar 2021 |
| India | 329 | 48.2 | 6.80 | Pune | 28 Mar 2021 |
| England | 322/9 | 50.0 | 6.44 | Pune | 28 Mar 2021 |
| India | 317/5 | 50.0 | 6.34 | Pune | 23 Mar 2021 |
| England | 251 | 42.1 | 5.95 | Pune | 23 Mar 2021 |
| Player | Mat | Runs | HS | 100 | 50 | |
| Virat Kohli (Ind) | 5 | 231 | 80* | 0 | 3 | |
| JC Buttler (Eng) | 5 | 172 | 83* | 0 | 2 | |
| DJ Malan (Eng) | 5 | 148 | 68 | 37.00 | 0 | 1 |
| JJ Roy (Eng) | 5 | 144 | 49 | 28.80 | 0 | 0 |
| SS Iyer (Ind) | 5 | 121 | 67 | 0 | 1 | |
| JM Bairstow (Eng) | 5 | 118 | 40* | 0 | 0 | |
| RR Pant (Ind) | 5 | 102 | 30 | 0 | 0 |
| Player | Wkts | Mat | Runs | BBI |
| SN Thakur (Ind) | 8 | 5 | 168 | 3/42 |
| JC Archer (Eng) | 7 | 5 | 155 | 4/33 |
| Mark Wood (Eng) | 5 | 4 | 127 | 3/31 |
| B Kumar (Ind) | 4 | 5 | 115 | 2/15 |
| W Sundar (Ind) | 4 | 5 | 138 | 2/29 |
| Adil Rashid (Eng) | 4 | 5 | 148 | 1/14 |
| CJ Jordan (Eng) | 4 | 5 | 198 | 2/35 |
| Player | Runs | Venue | Date |
| JC Buttler (Eng) | 83* | Ahmedabad | 16 Mar 2021 |
| Virat Kohli (Ind) | 80* | Ahmedabad | 20 Mar 2021 |
| Virat Kohli (Ind) | 77* | Ahmedabad | 16 Mar 2021 |
| Virat Kohli (Ind) | 73* | Ahmedabad | 14 Mar 2021 |
| DJ Malan (Eng) | 68 | Ahmedabad | 20 Mar 2021 |
| SS Iyer (Ind) | 67 | Ahmedabad | 12 Mar 2021 |
| RG Sharma (Ind) | 64 | Ahmedabad | 20 Mar 2021 |
| SA Yadav (Ind) | 57 | Ahmedabad | 18 Mar 2021 |
| Ishan Kishan (Ind) | 56 | Ahmedabad | 14 Mar 2021 |
| Player | 6s | Mat | Runs | HS |
| JC Buttler Eng) | 10 | 5 | 172 | 83* |
| Virat Kohli (Ind) | 9 | 5 | 231 | 80* |
| JJ Roy (Eng) | 6 | 5 | 144 | 49 |
| RG Sharma (Ind) | 6 | 3 | 91 | 64 |
| HH Pandya (Ind) | 6 | 5 | 86 | 39* |
| DJ Malan (Eng) | 5 | 5 | 148 | 68 |
| SA Yadav (Ind) | 5 | 3 | 89 | 57 |
| Player | 50s | Mat | Runs | HS |
| Virat Kohli (Ind) | 3 | 5 | 231 | 80* |
| JC Buttler (Eng) | 2 | 5 | 172 | 83* |
| SS Iyer (Ind) | 1 | 5 | 121 | 67 |
| Ishan Kishan (Ind) | 1 | 2 | 60 | 56 |
| SA Yadav (Ind) | 1 | 2 | 89 | 57 |
| DJ Malan (Eng) | 1 | 5 | 148 | 68 |
| RG Sharma (Ind) | 1 | 3 | 91 | 64 |
| Player | 100s | Mat | Runs | HS |
| Team | Score | Ovrs | RR | Venue | Date |
| India | 224/2 | 20.0 | 11.20 | Ahmedabad | 20 Mar 2021 |
| England | 188/8 | 20.0 | 9.40 | Ahmedabad | 20 Mar 2021 |
| India | 185/8 | 20.0 | 9.25 | Ahmedabad | 18 Mar 2021 |
| England | 177/8 | 20.0 | 8.85 | Ahmedabad | 18 Mar 2021 |
| India | 166/3 | 17.5 | 9.30 | Ahmedabad | 14 Mar 2021 |
| England | 164/6 | 20.0 | 8.20 | Ahmedabad | 14 Mar 2021 |
| India | 158/2 | 18.2 | 8.61 | Ahmedabad | 16 Mar 2021 |
| India | 156/6 | 20.0 | 7.80 | Ahmedabad | 16 Mar 2021 |
| England | 130/2 | 15.3 | 8.38 | Ahmedabad | 12 Mar 2021 |
| India | 124/7 | 20.0 | 6.20 | Ahmedabad | 12 Mar 2021 |
| Player | Mat | Runs | HS | 100 | 50 | |
| Joe Root (Eng) | 4 | 368 | 218 | 1 | 0 | |
| RG Sharma (Ind) | 4 | 345 | 161 | 1 | 1 | |
| RR Pant (Ind) | 4 | 270 | 101 | 54.00 | 1 | 2 |
| Ben Stokes (Eng) | 4 | 203 | 82 | 0 | 2 | |
| R Ashwin (Ind) | 4 | 189 | 106 | 1 | 0 | |
| Washington Sundar (Ind) | 3 | 181 | 96* | 0 | 2 | |
| Virat Kohli (Ind) | 4 | 172 | 72 | 0 | 2 | |
| OJ Pope (Eng) | 4 | 153 | 34 | 0 | 0 |
| Player | Wkts | Mat | Runs | BBI |
| R Ashwin (Ind) | 32 | 4 | 471 | 6/61 |
| Axar Patel (Ind) | 27 | 3 | 286 | 6/38 |
| MJ Leach (Eng) | 18 | 4 | 517 | 4/54 |
| James Anderson (Eng) | 8 | 3 | 127 | 3/17 |
| Moeen Ali (Eng) | 8 | 1 | 226 | 4/98 |
| JE Root (Ind) | 6 | 4 | 141 | 5/8 |
| Ishant Sharma (Ind) | 6 | 4 | 160 | 3/76 |
| Player | Runs | Venue | Date |
| JE Root (Eng) | 218 | Chennai | 05 Feb 2021 |
| RG Sharma (Ind) | 161 | Chennai | 13 Feb 2021 |
| R Ashwin (Ind) | 106 | Chennai | 13 Feb 2021 |
| RR Pant (Ind) | 101 | Ahmedabad | 04 Mar 2021 |
| Washington Sundar (Ind) | 96* | Ahmedabad | 04 Mar 2021 |
| RR Pant (Ind) | 91 | Chennai | 05 Feb 2020 |
| Dom Sibley (Eng) | 87 | Chennai | 05 Feb 2021 |
| Washington Sundar (Ind) | 85* | Chennai | 05 Feb 2021 |
| Ben Stokes (Eng) | 82 | Chennai | 05 Feb 2021 |
| CA Pujara (Ind) | 73 | Chennai | 05 Feb 2021 |
| Virat Kohli (Ind) | 72 | Chennai | 05 Feb 2021 |
| Player | 6s | Mat | Runs | HS |
| RR Pant (Ind) | 10 | 4 | 270 | 101 |
| Moeen Ali (Eng) | 5 | 1 | 49 | 43 |
| RG Sharma (Ind) | 5 | 4 | 345 | 161 |
| Ben Stokes (Eng) | 5 | 4 | 203 | 82 |
| Washington Sundar (Ind) | 3 | 3 | 181 | 96* |
| Joe Root (Eng) | 2 | 4 | 368 | 218 |
| Mhd Siraj (Ind) | 2 | 1 | 20 | 16* |
| Player | 50s | Mat | Runs | HS |
| RR Pant (Ind) | 2 | 4 | 270 | 101 |
| Virat Kohli (Ind) | 2 | 4 | 172 | 72 |
| Ben Stokes (Eng) | 2 | 4 | 203 | 82 |
| Washington Sundar (Ind) | 2 | 3 | 181 | 85* |
| Dom Sibley (Eng) | 1 | 4 | 134 | 87 |
| CA Pujara (Ind) | 1 | 4 | 133 | 73 |
| Shubhman Gill (Ind) | 1 | 4 | 119 | 50 |
| AM Rahane (Ind) | 1 | 4 | 112 | 67 |
| RG Sharma (Ind) | 1 | 4 | 345 | 161 |
| Player | 100s | Mat | Runs | HS |
| Joe Root (Eng) | 1 | 4 | 368 | 218 |
| RG Sharma (Ind) | 1 | 4 | 345 | 161 |
| R Ashwin (Ind) | 1 | 4 | 189 | 106 |
| RR Pant (Ind) | 1 | 4 | 270 | 101 |
| Team | Score | Inns | Ovrs | RR | Venue | Date |
| England | 578/10 | 1st | 190.1 | 3.03 | Chennai | 05 Feb 2021 |
| India | 365/10 | 2nd | 114.4 | 3.18 | Ahmedabad | 04 Mar 2021 |
| India | 337/10 | 2nd | 95.5 | 3.51 | Chennai | 05 Feb 2021 |
| India | 329/10 | 1st | 95.5 | 3.43 | Chennai | 13 Feb 2021 |
| India | 286/10 | 3rd | 85.5 | 3.33 | Chennai | 13 Feb 2021 |
| England | 205/10 | 1st | 75.5 | 2.70 | Ahmedabad | 04 Mar 2021 |
| India | 192 | 4th | 58.1 | 3.30 | Chennai | 05 Feb 2021 |
| England | 178 | 3rd | 46.3 | 3.82 | Chennai | 05 Feb 2021 |
| England | 164 | 4th | 54.2 | 3.01 | Chennai | 13 Feb 2021 |